Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder
Study
Psilocybin to improve drinking outcomes in patients with alcohol use disorder.
Results
93 participants were randomized into a double-blind treatments of psilocybin and a placebo and evaluated across 32 weeks. Percentage of heavy drinking days for the psilocybin group was 9.7%, whereas the placebo group was 23.6%. Mean daily alcohol consumption (i.e. number of drinks per day) was lower in the psilocybin group.
Discussion
Combining psilocybin with psychotherapy showed significant decreases in number of heavy drinking days and number of drinks.
Citation
Bogenschutz MP, Ross S, Bhatt S, et al. Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2022;79(10):953–962. doi:10.1001/jamapsychiatry.2022.2096